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The “many faces” of B12 deficiency include neurologic symptoms such as numbness and tingling in the hands and feet, muscle cramps, dizziness, cognitive disturbances, difficulty walking, erectile dysfunction, as well as fatigue and psychiatric symptoms like depression and even psychosis.” In addition to these more spectacular symptoms, B12 deficiency over time is associated with a rise in homocysteine in the blood, an amino acid that, when elevated, leads to a hardening and thickening of artery walls
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Sertraline, an antidepressant, induces apoptosis in hepatic cells through the mitogen-activated protein kinase pathway
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