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Other Natural Compounds Targeting HIF-1α (Sulforaphane, Epigallocatechin Gallate, Salternamide A, Verbascoside, Ilexgenin A, Desferrioxamine, Worenine, Sesamin, Genipin, Brusatol, Panaxadiol) Another study examined the effect of sulforaphane, a naturally occurring substance often present in broccoli,78 on the expression of HIF-1α in HCT116 (colon cancer) and AGS (gastric cancer) cells
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conducted a phase II prospective, randomized, double-blinded, placebo-controlled study aimed at determining the efficacy and safety of the novel whole tomato-based food supplement in reducing LUTS of patients with histologically validated BPH (via PBX) [166,167]
