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coli due to sympathetic activation receptor agonist on changes in the gut bacterium and the underlying mechanisms ( Sodium-glucose cotransporter protein (SGLT2) inhibitor that inhibits glucose reabsorption by inhibiting sodium-glucose cotransporter protein 2 in the proximal renal tubule ( In an animal study, it was explored whether the effects of Sacubitril/Valsartan on DN were related to the gut microbiota and associated plasma metabolic profile

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Random allocation was applied to assign animals to experimental groups