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During reperfusion, the ischemic tissues release pro-inflammatory cytokines, such as tumor necrosis factor-alpha (TNF- α ), interleukin-1β (IL-1β), and interleukin-6 (IL-6), which contribute to the recruitment of neutrophils, macrophages, and other immune cells to the site of injury (Pawluk et al., 2020

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Vitamin B12 requires the active form of folate to be absorbed by the body