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Other ITCs, such as SIN, demonstrated anticonvulsant, antioxidant, and anti-inflammatory effects in pentylenetetrazole-treated rats by delaying seizure onset, improving memory, increasing antioxidant enzyme levels (SOD and CAT), and downregulating pro-inflammatory genes (Il1b and Nlrp3) [218]
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The preparation is standardised prior to use, allowing researchers to work with a consistent peptide composition and eliminating variability associated with solution preparation