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Glutathione S-transferase inhibitor NBDHEX induces ROS-dependent immunogenic cell death and enhances PD-1 blockade in DLBCL | Cell Communication and Signaling | Springer Nature Link

While Vit C is a direct antioxidant, its pro-oxidant potential in specific conditions needs to be considered

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Interestingly, we also found that Gpx3 is the primary activator of Cap1 upon exposure to organic peroxides, including lipid peroxides, but not to H 2 O 2 (Figs 4A, 4B, 6A, 6C and 6D)